The traditional friendship and cooperation between the People's Republic of China and the Republic of Guinea enjoyed steady development in 2010.

The two countries maintained exchanges at various levels. In December, President Hu Jintao, Premier Wen Jiabao and Foreign Minister Yang Jiechi sent messages of congratulations respectively to their Guinean counterparts, i.e., the newly elected President Alpha Condé, new Prime Minister Mohamed Saïd Fofana, Minister of Foreign Affairs and Overseas Compatriots Edouard Gnakoye Lama on their assumption of office. In October, Minister of Economy and Finance of Guinea's transitional government Kerfalla Yansane led a delegation to attend Guinea's National Pavilion Day at the Shanghai World Expo 2010.

Health cooperation between the two countries continued to develop. China sent its 22nd medical team to Guinea in August.