The relations between the People's Republic of China and the Republic of Guinea-Bissau maintained steady growth in 2013.

The two countries maintained a sound momentum of friendly exchanges. In March, Guinea-Bissau's Interim President Manuel Serifo Nhamajo sent a congratulatory letter to President Xi Jinping on his election, and Prime Minister of the transitional government Rui Duarte de Barros and President of the National People's Assembly Ibraima Sori Djaló sent congratulatory letters to Premier Li Keqiang and NPC Chairman Zhang Dejiang respectively on their assumption of office. On 23 April, Prime Minister of the transitional government de Barros sent a letter of sympathy to Premier Li over the earthquake that struck Lushan, Sichuan Province. In November, Prime Minister of the transitional government de Barros led a delegation to the Fourth Ministerial Conference of the Forum on Trade and Economic Cooperation between China and Portuguesespeaking Countries (Macao). In August, Minister of Public Health of the transitional government Agostinho Cá came to China for the Ministerial Forum of China-Africa Health Development. In September, Minister of Foreign Affairs, International Cooperation and Overseas Communities of the transitional government Fernando Delfim da Silva attended the formal consultations between Chinese and African Foreign Ministers on the sidelines of the UN General Assembly in New York. In October, Minister of Fisheries and Fishery Resources of the transitional government Mário Lopes da Rosa attended the Joint Fisheries Committee meeting in China. In December, Minister of Agriculture of the transitional government Nicolau Santos visited China.

In July, China's new Ambassador to Guinea-Bissau Wang Hua presented his credentials to Guinea-Bissau's Interim President Manuel Serifo Nhamajo.

Economic and trade cooperation between China and Guinea-Bissau achieved positive results. A number of projects with Chinese assistance were concluded successfully and handed over to Guinea-Bissau, including renovation of the National Stadium "September the 24th", renovation and expansion of the Presidential Palace and the project of the National School of Health.